PCNA and GSK3β interact with each other to regulate H1299 lung adenocarcinoma cells apoptosis
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چکیده
منابع مشابه
hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells
c-FLIP (cellular FLICE-inhibitory protein) is the pivotal regulator of TRAIL resistance in cancer cells, It is a short-lived protein degraded through the ubiquitin/proteasome pathway. The discovery of factors and mechanisms regulating its protein stability is important for the comprehension of TRAIL resistance by tumor cells. In this study, we show that, when H1299 lung adenocarcinoma cells are...
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ژورنال
عنوان ژورنال: Neoplasma
سال: 2020
ISSN: 1338-4317
DOI: 10.4149/neo_2019_190116n48